Researchers from the University of Texas Southwestern Medical Center (Dallas) have reported that long-term anti-retroviral therapy (ART) used for the treatment of HIV-1 infection can cause ptosis and external ophthalmoplegia (progressive paralysis of the extraocular muscles. Thus, the authors of the study have recommended that clinicians should be aware of potential adverse effects of the treatment such as myopathic complications, weakness, neuropathy, deafness etc.