Pharmaceuticals are increasing for production of AzaSite (azithromycin ophthalmic solution) 1 percent in the US and Canada in response to the manufacturing supply shortage of erythromycin ophthalmic ointment (0.5%). Erythromycin ophthalmic ointment is approved for prophylaxis of ophthalmia neonatorum, a form of bacterial conjunctivitis that may be contracted by newborns during delivery. The ointment was placed on the FDA’s Drug Shortage list.

The FDA has approved a new antibacterial eyedrop called Besivance for the treatment of a contagious eye infection called bacterial conjunctivitis, commonly known as “pinkeye.” Symptoms of bacterial conjunctivitis include red eyes, swelling, eyelids sticking together, itching, watering, and a white or yellow sticky discharge from the eyes. Bacterial conjunctivitis generally runs its course in seven to 14 days. Although this infection is common among kids, it can also affect people of other ages.

InSite Vision Incorporated has announced that the U.S. Food and Drug Administration (FDA) Dermatologic and Ophthalmic Drugs Advisory Committee has voted unanimously to recommend approval of Bausch & Lomb’s besifloxacin ophthalmic suspension, 0.6%, for the treatment of bacterial conjunctivitis, a product that utilizes InSite Vision’s DuraSite® patented drug delivery system. DuraSite is a synthetic polymer of cross-linked polyacrylic acid that stabilizes small molecules in an aqueous matrix, allowing for targeted and sustained administration. DuraSite enables a less frequent dosing schedule, increased patient compliance, and increased efficacy.