During the 5th International Congress of Corneal Cross Linking for Keratoconus in Germany, Avedro presented encouraging clinical results for treating keratoconus, a progressive disease of the cornea of the eye. The procedure, known as Keraflex® KXL, is non-incisional and reshapes the cornea without removing any tissue. Keratoconus, or KC, is a cone-shaped protrusion and distortion of the cornea that typically begins in the teenage years or 20’s and afflicts millions of people around the world.

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According to a study conducted at Mayo Clinic, Rochester, Minn., has found that laser eye surgery that corrects vision does not lead to later problems with the cornea – at least not after nine years . Two types of laser surgery—photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK)—are often used to correct refractive errors such as nearsightedness.

Researchers from Emory University in Atlanta have developed a new treatment for corneal disease called Keratoconus. This special procedure stabilizes the cornea, while reversing some of the other permanent changes in the integrity and curvature. The treatment called Corneal Collagen Cross-Linking includes few steps. Firstly, patients are given a topical anesthetic to avoid discomfort during the treatment. Removal of a thin layer of cells from the top of the cornea follows. Then, riboflavin drops are placed into the eye. This saturates the cornea for half an hour. After that, the eye is exposed to Ultra Violet A light for 30 more minutes. The UVA light interacts with the riboflavin to form chemical bonds between the collagen molecules in the cornea, stiffening it and helping it to retain a rounder shape. A soft contact lens is placed in the eye to protect the cornea. It is removed after three to five days. As the cornea heals and stiffens, the curvature gradually improves